My mom lives by a Mexican family that makes an ointment for nerve damage and arthritis. It's topical and applied with a cotton ball. I put some on my sciatic nerve area and had instant relief!! For the life of me I cannot find the recipe online and the family seems unwilling to relinquish their recipe. Everything I read is about drinking it not applying it.
Does anyone know of a recipe for a topical solution using Yerba Mate?
Does anyone know of a recipe for a topical solution using Yerba Mate?
-
Re: Yerba Mate Ointment?
Mon, September 10, 2007 - 3:46 PMNaturally occurring proteasome inhibitors from mate tea (Ilex paraguayensis) serve as models for topical proteasome inhibitors.
J Invest Dermatol. 2005 Aug;125(2):207-12. Arbiser JL, Li XC, Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia 30322
Proteasome inhibitors have emerged as a clinically important therapy for neoplastic disease, with velcade, an organoboron compound used extensively in multiple myeloma. Recently, (-)-epigallocatechin gallate has been found to be a potent inhibitor of the proteasomal chymotrypsin -like activity. Other compounds that inhibit angiogenesis and are active as chemopreventive agents, such as curcumin, also inhibit proteasome activity. We have screened natural product extracts and found that extracts of yerba mate tea (Ilex paraguayensis) inhibit the growth of these endothelial cells. The extract was fractionated and found to have novel cinnamate esters that inhibit proteasome activity. Based upon these findings, preclinical and clinical trials of topical cinnamate esters as proteasome inhibitors are warranted for psoriasis and other inflammatory disorders.
